Okazaki Domain samurai Inaba Gotaro accidentally killed a superior while trying to save his beloved geisha, Ko-en. On the run, they were rescued by the actor Nakamura Utaemon, but Ko-en was taken by the Hatamoto, Ono Issai. Gotaro, who fell off a cliff, was saved by the Dutch-trained doctor, Shibarai Ryokai, and his daughter Oume. While traveling to Edo, they met Utaemon in Mishima, who was suffering from a serious eye disease. Ryokai’s treatment saved Utaemon from blindness, and a strong friendship was formed among the three.